منابع مشابه
Acting like Actin
The crawling movement of eukaryotic cells requires establishment of cell polarity, extension of the leading edge, attachment to the substratum, and retraction of the cell body. Each of these events depends on the dynamics of the actin cytoskeleton that are orchestrated by a host of signaling molecules and actin-binding proteins. Indeed, amoeboid cell motility involves so many biochemical compon...
متن کاملActuators Acting without Actin
Plant actuators move organs, allowing the plant to respond to environmental cues or perform other mechanical tasks. In Cardamine hursuta the dispersal of seeds is accomplished by explosive opening of the fruit. The biomechanical mechanism relies on a complex interplay between turgor regulation and cell wall mechanical properties.
متن کاملDNA acting like RNA.
Over the last decade or so, secondary non-B-DNA structures such as G-quadruplexes and i-motifs have come into focus as biologically functioning moieties that are potentially involved in telomeric interactions and the control of gene expression. In the present short review, we first describe the structural and dynamic parallels with complex RNA structures, including the importance of sequence an...
متن کاملFtsA forms actin-like protofilaments.
FtsA is an early component of the Z-ring, the structure that divides most bacteria, formed by tubulin-like FtsZ. FtsA belongs to the actin family of proteins, showing an unusual subdomain architecture. Here we reconstitute the tethering of FtsZ to the membrane via FtsA's C-terminal amphipathic helix in vitro using Thermotoga maritima proteins. A crystal structure of the FtsA:FtsZ interaction re...
متن کاملThe bacterial actin-like cytoskeleton.
Recent advances have shown conclusively that bacterial cells possess distant but true homologues of actin (MreB, ParM, and the recently uncovered MamK protein). Despite weak amino acid sequence similarity, MreB and ParM exhibit high structural homology to actin. Just like F-actin in eukaryotes, MreB and ParM assemble into highly dynamic filamentous structures in vivo and in vitro. MreB-like pro...
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ژورنال
عنوان ژورنال: Science
سال: 2010
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.330.6009.1289-b